Cryopreservation and storage of spermatozoa

Title: Cryopreservation and storage of spermatozoa
Creator: McLaughlin, Eileen A.; Pacey, Allan A.
Relation: Textbook of Assisted Reproductive Technologies: Laboratory and Clinical Perspectives p. 311-321
Relation: http://informahealthcare.com/doi/abs/10.3109/9780203092934.023
Publisher: Informa Healthcare
Resource Type: book chapter
Date: 2009
Description: Human semen cryopreservation has a long history that stretches back over 200 years to the first recorded experiments involving cooling followed by successful rewarming of spermatozoa in snow. Despite this early success, it was not until the fortuitous discovery of glycerol as a cryoprotectant, and the subsequent live birth of a calf in the early 1950s, that cryopreservation of human semen for assisted reproduction became a realistic option. The ability to store human semen greatly improved the flexibility of donor insemination treatment,resulting in the first live human births in 1953 and donor insemination (DI) became a mainstay of fertility treatment for the next 40 years. More recently, sperm cryopreservation has become an essential part of fertility preservation for young men who face the possibility of sterility as a consequence of the treatments given to combat cancer.
Subject: fertility; embryology; oocyte; assisted reproduction; IVF; cryoprotection
Identifier: http://hdl.handle.net/1959.13/918081
Identifier: uon:8504
Identifier: ISBN:9780415448949
Language: eng

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